Oxidative Metabolism of Phenylacetic Acid by Penicillium chrysogenumQ-176
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منابع مشابه
Oxidative Metabolism of Phenylacetic Acid by Penicillium chrysogenum Q-176. Part 6. The Production of Homogentisic Acid by a Mutant Strain Induced from Pen. chrysogenum
Penicillium chrysogenurn Q-176に よPhenylacetic Acidの 酸化的代謝 に關す る研 究(第6報) Pen. chyysognum Q-176 の1変 異 種 に よ るHomogentisic Acidの 生成 に つ い て (そ の2)Phenylacetic Acid代 謝 異 常 菌 株 の菌 学 的性 質 磯 野 正 雄(武田 薬品工業株式会社大阪工場) 昭 和28年10月24日 受 理 Oxidative Metabolism of Phenylacetic Acid by Penicillium chrysogenum Q-176. Part 6. The Production of Homogentisic Acid by a Mutant Strain Induced from Pen. chrysogenum Q-17...
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Penicillium chrysogenum utilizes phenylacetic acid as a side chain precursor in penicillin G biosynthesis. During industrial production of penicillin G, phenylacetic acid is fed in small amounts to the medium to avoid toxic side effects. Phenylacetic acid is taken up from the medium and intracellularly coupled to 6-aminopenicillanic acid. To enter the fungal cell, phenylacetic acid has to pass ...
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The media most useful for penicillin production contain corn-steep liquor (CSL), which has a high organic acid content. Such media usually contain about 5 mg./ml. lactic acid and rather less than 0-5 mg./ml. acetic acid. It has been found beneficial to include organic acids, especially the two mentioned, in synthetic media for penicillin production (Stone & Farrell, 1946; Jarvis & Johnson, 1947...
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Baker, W., Harborne, J. B. & Ollis, W. D. (1952). J. chem. Soc. p. 3215. Bergstrom, S. & Hansson, G. (1951). Acta phy8iol. scand. 22, 87. Billen, D. & Lichstein, H. C. (1949). J. Bact. 57, 267. Block, R. J., Durrum, E. L. & Zweig, G. (1958). A Manual of Paper Chromatography and Paper Electrophoresi8, p. 235. New York: Academic Press Inc. Bush, H., Hulbert, R. B. & Potter, V. R. (1952). J. biol....
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ژورنال
عنوان ژورنال: Journal of the agricultural chemical society of Japan
سال: 1953
ISSN: 0002-1407,1883-6844
DOI: 10.1271/nogeikagaku1924.27.193